Kyle Farmer and the Reds seek 1st win at Fenway Park since Game 7 of the 1975 World Series

Previewing the pitching matchups: Reds vs. Red Sox

Reds starting pitcher Luis Castillo vs. Red Sox starting pitcher Michael Wacha

It's La Piedra Day, as Luis Castillo (1-2 4.35 ERA) battles longtime Cincinnati rival Michael Wacha (3-0 2.83 ERA) of the Red Sox. In his last two starts, Castillo has displayed why he's the undeniable ace of the Cincinnati Reds staff.

Tossing 11 innings, Castillo has fanned 11 batters against just one free pass. Additionally, the right-hander has not allowed a gopher ball in his last two outings. It took him a little over a month to get back into the starting rotation, but this is what fans expect from Luis Castillo.

Don't be surprised if Boston manager Alex Cora loads his lineup with left-handed bats tonight. Castillo has completely abused right-handed hitters, holding them to an anemic .156/.174/.222 slash line to being the 2022 season.

You can spare the introductions when it comes to the Cincinnati Reds and Michael Wacha. The former St. Louis Cardinal has absolutely frustrated the Reds over his career.

The right-hander owns a 12-2 record with a sparkling 2.81 ERA in 23 games, including 19 starts, versus Cincinnati. However, Reds legend Joey Votto has been immune to his curse. Cincinnati's long-time first baseman is slashing .364/.431/.659 with five doubles and two homers in 44 career at-bats versus Wacha.

Reds starting pitcher Hunter Greene vs. Red Sox starting pitcher Garrett Whitlock

Rookie Hunter Greene (2-6 5.89 ERA) toes the rubber in Wednesday's night series finale, while Garrett Whitlock (1-1 3.49 ERA) gets the call for Alex Cora's club. After allowing just one homer over his last 13 innings, Greene was taken deep three times in five frames against the Chicago Cubs his last time on the mound.

As Reds Country knows all too well, the 22-year-old right-hander is susceptible to the long ball. The 15 round-trippers surrendered are the most in the National League this season. Needless to say, this will be an incredibly challenging start for the Reds rookie.

Don't expect to see Boston starter Garrett Whitlock go too deep in Wednesday night's contest. The right-hander's longest appearance this season has been six innings, and he's gone less than five frames in four of his seven starts this year.